Current Research Pertaining to the Correlation of Prion Proteins and Alzheimer's Disease

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Published: Nov 21, 2023

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Rikhil Chitimilla
University of Illinois Urbana-Champaign

Abstract

At present, there are around 50 million AD patients worldwide and this number is projected to double every 5 years and will increase to reach 152 million by 2050. (National Library of Medicine). This neurodegenerative disease has been known to cause cognitive impairment and memory loss. In recent research ti seems that this degenerative disease is being correlated with the accumulation of the amyloid-beta (Aß) peptide as well as the prion protein ( P r C ) . (PrPC) has been discovered to have inhibitory properties on the Beta-Secretase enzyme (BACE1). The inhibition of BACE1 leads to the essential deprivation of the rate-limiting step, which results in the increase of amyloid-beta.

Article Details

Issue
Vol. 6 No. 2 (2023): Brain Matters
Section
Micro-Articles
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Author Biography

Rikhil Chitimilla, University of Illinois Urbana-Champaign

Hello, my name is Rikhil Chitimilla, a current Junior majoring in MCB and planning to get my neuroscience certificate as well. In my spare time I enjoy going around campus and visiting restaurants that I haven't been at before. I love to cook and have been trying to get into baking as of recentlv. On campus I work as a TA for LAS 101 and as an RA in Townsend Hall. Brain matters has really allowed me to conduct my own research and explore my own interests in the field of neuroscience.