GLP-1 Receptor Agonists
A Potential Treatment for AUD
Abstract
Alcohol use disorder (AUD) is a chronic substance use disorder characterized by uncontrolled alcohol consumption. According to the National Institute on Alcohol Abuse and Alcoholism, it affects roughly 28.9 million people in the US (2024) and was linked to 2.6 million preventable deaths worldwide in 2019 (World Health Organization, 2024). One major roadblock in treating AUD is the limited availability of prescribable medications-only three are currently approved in the United States. Consequently, a major focus of current research is finding suitable therapeutic agents. Recent clinical studies suggest GLP-1 receptor agonists (GLP-1 RAs), which are normally used to treat Type 2 diabetes, may be potential candidates.
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Published
2025-07-14